HdrOzone
Hydronium & Ozone & Hydrogen Peroxide & Gas Plasma Sterilization Device

Hydrogen Peroxide (H2O2) + Ozone (O3) Heavy-Molecule (Hydronium) Sterilization System
HdrOzone

A PARADIGM SHIFT IN STERILIZATION TECHNOLOGY !

4th Generation Hybrid NEW Technology = HdrOzone

Hydronium & Ozone & Hydrogen Peroxide & Gas Plasma & Low-Temperature Sterilization Device

B SCIENCE® HdrOzone®

Hydronium + O3 + H2O2 + Plasma

Next-Generation Sterilization Platform

English 1445 Kb

Catalog

English 399 Kb

DataSheet

English 2638 Kb

Presentation

English 140 Kb

Specification
B Science

Hydronium + O3 + H2O2 + Plasma

THE MOST EFFECTIVE and SAFE SOLUTION for Lumened Instrument Sterilization

A NEW ERA IN STERILIZATION HAS BEGUN!

NO "Diameter and Length" LIMITATIONS under FULL LOAD for All Types of "Lumened Instruments".
(Ø 2 mm Internal Diameter, Minimum 15 m Length)

HdrOzone sterilization system is designed for the safe sterilization of heat- and moisture-sensitive medical instruments, plastics, lumened devices, electromechanical surgical equipment, as well as complex and long-lumen devices such as single- and multi-channel flexible endoscopes.

It can be safely used for the sterilization of long and complex endoscopes, as well as multi-channel flexible lumen endoscopes with up to 4 channels and 4.5 m length. It has verified sterilization capability for lumens down to Ø 2 mm in diameter and up to 15 meters in length.

HdrOzone sterilization device is a low-temperature (37°C–45°C) dual-sterilant sterilization system using [Hydrogen Peroxide (H2O2) and Ozone (O3)] with cold plasma capability.

HdrOzone: Safe Sterilization Process

HdrOzone sterilization features vacuum-based gas sterilization technology. It eliminates the lumen, diameter, and length restrictions common to standard hydrogen peroxide sterilizers.

It delivers significantly higher efficacy for complex lumened instruments compared to conventional H2O2 plasma systems. Beyond chemical-reaction sterilization, the system generates highly active hydroxyl radicals, heavy molecules, and plasma activity. It exhibits the gas-phase sterilization characteristics of techniques such as EO. It does not cause corrosion or leave toxic residues on sterilized products.

Lumen Program
HdrOzone Sterilization Device Lumen Program

Operating with a 58%–60% Hydrogen Peroxide (H2O2) solution and Medical-Grade Oxygen, the intelligent program design synergizes Ozone and H2O2 to achieve maximum sterilization efficacy at minimum active dosages.

HdrOzone Operating Principle: Sterilization is driven by the combined dynamic effect of H2O2, O3, and HYDRONIUM (HO3, HO4, H2O3, H2O4, HO5, OOH, H3O, etc.) heavy molecules, radicals, hydroxyls, and active ions.

HdrOzone Thanks to advanced process engineering, items processed in the sterilization device require no post-sterilization aeration and are immediately ready for use. Byproducts consist strictly of water vapor and oxygen, ensuring complete safety for healthcare personnel, patients, and the environment.

HdrOzone sterilization system uses pre-programmed, automated sterilization cycles that minimize human error. Unlike standard hydrogen peroxide sterilizers, there is no need to manually sort instruments or select complex specific cycles. Mixed loading (combining endoscopes with other materials) can be processed together, maximizing throughput while reducing sorting labor and operational costs. HdrOzone minimize cycle expenses, ensuring low operational costs. HdrOzone is effective against biofilms, microcracks, enclosed spaces, optics, and organic residues in lumened instruments.

HdrOzone Menu
HdrOzone Main Screen

The wide touchscreen display provides simple and fast operation with language selection and pre-defined program options for sterilization.

Complies with ISO 14937 standards.

Packaging characteristics: synthetic, cellulose-free materials such as polypropylene or Tyvek®; fabric, cellulose/paper, liquid sterilization, natural rubber, etc. are not suitable for this sterilization method.

HdrOzone heavy-molecule sterilization device operates using the Hydronium technique. The HdrOzone Device can also be used as a hydrogen peroxide sterilization device via dedicated H2O2 sterilizer function programs.

HdrOzone® Sterilization Device Operating Principle

The sterilization process is completed in 8 successive stages.

HdrOzone Operating Principle
HdrOzone Operating Principle

After the chamber temperature reaches the selected value:

  1. Vacuum phase: The sterilization chamber is evacuated to -600 to -900 mBar vacuum.
  2. Injection phase: Vaporization of the 58%–60% H2O2 concentration and injection into the sterilization chamber.
  3. Diffusion phase: Diffusion of hydrogen peroxide to the materials to be sterilized in the chamber.
    • Oxygen is introduced into the system, converted to ozone, and delivered into the chamber.
    • Hydrogen peroxide and ozone diffuse to the materials to be sterilized in the chamber.
    • ADSORPTION of hydronium and heavy molecules for sterilization.
    • Dilution of hydrogen peroxide in the sterilization chamber.
  4. Plasma phase: HRF COLD PLASMA is generated in the sterilization chamber under an atmospheric vacuum of -300 to -700 mBar.
  5. Ventilation-Aeration phase: The sterilization chamber returns to normal atmospheric pressure.
PROGRAMS
  • Provides simple and fast operation through language selection and pre-defined program options on the wide touchscreen.
  • In addition to its superior features, the HdrOzone Sterilization Device can also operate independently as a Hydrogen Peroxide Sterilization Plasma Device.
  • There are 5 programs in total: 2 HdrOzone Heavy-Lumen Programs and 3 H2O2 Programs.
  • In addition, a Half Cycle Validation Program is available on the validation page. The user interface is simple.
HYDROGEN PEROXIDE
Short 27 min

27 Minutes
H2O2

Long 45 min

45 Minutes
H2O2

Lumen 60 min

60 Minutes
H2O2

HDROZONE
Load 70 min

70 Minutes
H2O2 + O3 + Hydronium

Long Lumen 95 min

95 Minutes
H2O2 + O3 + Hydronium

HDROZONE® Lumen Sterilization (PCD)

The HdrOzone Sterilization Device sterilizes medical products and similar items, excluding conventional disposable materials. No boosters or auxiliary accessories are required for complex lumened devices.

Endoscopes
Rigid Endoscopes Flexible Endoscopes
Laryngoscopes
Arthroscopes
Laparoscopes
Trocar Cannulas
Trocar Sheaths
Resectoscopes
etc.
Bronchoscopes
Ureteroscopes
Hysteroscopes
Cystoscopes
Choledochoscopes
etc.
Devices & Instruments
Implants
Defibrillator Paddles
Electrocautery Tools
Esophageal Dilators
Cryo-Probes
Doppler Probes
ICP Transducer Cables
Endoscopic Accessories
etc.
Fiber Optic Cables
Laser Handpieces
Fiber Accessories
Ophthalmic Lenses
Radiotherapy Instruments
Surgical Power Tools
Drills & Cutters
Ultrasound Probes
Video Cameras & Adapters
etc.
DBD Plasma
HdrOzone DBD Cold Plasma
Does Not Cause Corrosion
B Science
HdrOzone Inspection Report   ISO 14937
HdrOzone Inspection Report ISO 14937
HdrOzone Positions and Result of the Microbiological Indicators
HdrOzone Chamber Test

4th Generation Hybrid Technology,
Hydronium Heavy-Molecule Low-Temperature Sterilizer

HdrOzone Platform Models and Technical Specifications
Model B3S125 B3S125 GI
TYPE BSCIENCE® HdrOzone BSCIENCE® HdrOzone GI HRF3000
DISPLAY 7" TOUCHSCREEN 10" TOUCHSCREEN
EXTERNAL DIMENSIONS (W-D-H) (mm) 730 x 955 x 1980 730 x 955 x 1980
CHAMBER INTERNAL DIMENSIONS (W-D-H) (mm) 440 x 500 x 700 440 x 500 x 700
CHAMBER VOLUME (L) 154 154
CHAMBER VOLUME (Usable L) 134 134
H2O2 CARTRIDGE SOLUTION VOLUME 120-150 cc 120-150 cc
MAXIMUM POWER (Watt) 3200 W 3200 W
OPERATING VOLTAGE 220/230 VAC, 50/60 Hz 220/230 VAC, 50/60 Hz
EXTERNAL FRAME MATERIAL 304/ESC Powder 304/ESC Powder
CHAMBER MATERIAL STAINLESS STEEL 304/316 STAINLESS STEEL 304/316
WEIGHT 450 kg 450 kg
Oxygen Specification
External Oxygen Connection Hospital-grade Medical Oxygen
≥ 90%
Sterile H2O2 Agent Specification for HdrOzone
H2O2 Concentration Sterilization efficacy is available at a minimum H2O2 concentration of 45% and above
H2O2 Cartridge Specification 45%–60% H2O2 / 100 cc–150 cc / Safety-valve equipped
Cartridge Cycle Quantity 5-cycle, 6-cycle, and 10-cycle cassette options are available.
Cartridge Shelf Life 6/12 months from the date of manufacture when stored at 15–25 ˚C.
Waste H2O2 Drainage Feature Available (1 L disposable)
Packaging Products Used
Compatible Packaging Materials Tyvek® Sterilization Roll, Wrap Papers, Various Surgical and Container Systems
Incompatible Materials Fabric, cellulosic materials (paper, cloth), silver-coated materials, liquid sterilization, powder, copper, natural rubber, etc.
Indicators H2O2 Chemical and Biological Indicators are used in HDROZONE
MAINTENANCE
Vacuum Pump and Maintenance Intervals Vacuum pump oil is changed and the device is serviced every 6 months (300 cycles) and annually (600 cycles). A periodic maintenance kit is also available.
Other Technical Features The device is a mobile block-type unit and can be easily transported and installed using four wheels under the cabinet, two of which are lockable. It requires an external hospital-grade oxygen gas source (or medical cylinder) and an electrical outlet. No additional waste drainage system is required.

Comparison Table of Ethylene Oxide, Hydrogen Peroxide, and HdrOzone Sterilization Systems

Sterilization Method Ethylene Oxide VH2O2/HPGP
Hydrogen Peroxide
HdrOzone (H3O)
Sterilization Agent EO - C2H4O H2O2 H2O2 & O3 & Hydronium
Efficacy Effective Limited Efficacy Highly Effective on Lumened Products
Sterilization Time ~ 4-12 Hours ~ 65 Minutes ~ 70 Minutes (Load)
Sterilization Cost ~ 20.00* € ~ 16.00* € ~ 17.00* €
Cartridge Storage Condition Challenging Suitable Suitable
Hazard Level High Environmentally Sensitive Ecological
Sterilization Preparation Level Medium Long Short
Capacity High Capacity Limited Capacity High Capacity
Material Compatibility Mixed Materials Different Programs for Different Products Mixed Materials
Air and Environmental Pollution Risky Ecological Ecological
External Connection Required Not Required Required
Operating Temperature 37-55 ℃ 37-55 ℃ 37-45 ℃
Sterility Assurance Level (SAL) 10-6 10-6 10-6
Maintenance Expensive Reasonable Reasonable-Easy
Installation Challenging Easy Easy
Operating Principle ETO Only H2O2 Gas Vapor or Plasma Only 1- H2O2 2- H2O2 & O3 3- Hydronium
Diameter and Length Unlimited 1 mm Ø - 850 mm / 2 mm Ø 1200 mm Ø 0.1 mm - 50 cm / 2 mm Ø internal diameter min. 4.5 - 15 meters length
Residue on Product Risky No residue on product No residue on equipment and multi-channel long-lumen devices
Device Cost (based on 100 units) ~25 units ~55 units ~75 units
Total Score 7/18 8/18 16/18

The table compares sterilizers in terms of different parameters and features. Although each of the sterilization methods has its established characteristics, there are variables that should be considered from the end-user perspective.

The ranking shows that the most suitable sterilizer is the HdrOzone Sterilization Device with 16/18 points. Second, with 8/18 in terms of Cost and Capacity, is the Hydrogen Peroxide Gas Plasma Sterilizer. Third, with limited advantages and high risks, is the Ethylene Oxide Gas Sterilizer with 7/18.

Advantages of the HdrOzone® Sterilization Technique in Sterilization
  • The use of heavy molecules instead of hydroxyls alone in the new HdrOzone technology and technique.
  • H2O2 + O3 and gaseous hydronium (H3O) are used instead of condensed H2O2.
  • Comprehensive sterilization safety.
  • High biofilm efficacy.
  • Short sterilization cycle time.
  • Fast sterilization process under full load capacity.
  • Sterilization of all types of materials under full load.
  • Mixed-load capability.
  • There is no need to separate materials or sterilize them individually when loading long lumens, short lumens, loads, and other materials into the sterilization chamber!
  • There is no length limit for lumened materials!
  • Damp, non-wet materials can be sterilized. No product drying operation is required as with other hydrogen peroxide devices.
  • Completes the sterilization process at low temperature and humidity.
  • For sterilization of long and thin (1 mm * 100 cm) lumened devices, it sterilizes multiple items up to 15 meters (2 mm diameter) at full load without requiring a manufacturer declaration.
  • Suitable for temperature- and moisture-sensitive materials.
  • Since the final products are H2O and O2, there is no harm to the environment. It is a safe method for the environment and human health.
  • Suitable for sterilizing very long and thin-lumened flexible surgical instruments at full load.
  • A sterilization method that leaves no toxic residue.
  • Easy, convenient, and safe to use.
  • No auxiliary accessories such as boosters are required.
  • No aeration time is required.
  • Reduces material-selection errors to zero. Reduces the need for qualified personnel.
  • The unit sterilization cost per material and labor costs are low.
  • The HdrOzone device uses a standard H2O2 device cartridge.
  • Because sterilization in HdrOzone is performed at FULL load, cartridge consumption is one-third compared to standard H2O2 devices.
HdrOzone® Sterilization Device INSTALLATION REQUIREMENTS

Always transport the device using a pallet truck. From the unloading location to the installation location, move it using the device's wheels. Have the device installed by our Technical Service. After installation, the personnel who will operate the device are trained and instructed on its operation.

For Installation;

  • A grounded 220 V AC outlet is required.
  • The installation area must be ventilated. The ambient temperature must be maintained between +15 °C and +35 °C.
  • There must be at least 60 cm of clearance on the rear and sides of the device.
  • A medical oxygen (O2) source of at least 2 bar is required. An oxygen cylinder or hospital oxygen supply can be used. The medical oxygen concentration must be greater than 90%.
  • An exhaust connection must be available in the wall for the HdrOzone device.
  • The H2O2 solutions to be used must be stored in a cool place.

BScience HdrOzone
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